Upregulated ATG4B predicts poor prognosis and correlates with angiogenesis in osteosarcoma

Background Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents. Between 35 and 45% of these patients do not respond to standard chemotherapeutic treatments, resulting in a very low 5-year survival rate of only 5–20%. This resistance often leads to treatment failure a...

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Bibliographic Details
Main Authors: Elzahraa Ibrahim Mohamed Khalil, Fatma El Zahraa Ammar Mohamed, Rehab Kamal Mohamed
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
Online Access:https://doi.org/10.1186/s43046-025-00269-z
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