Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival

Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival

Abstract Background The immune evasion and prolonged survival of Staphylococcus aureus (S. aureus) within macrophages are key factors contributing to the difficulty in curing osteomyelitis. Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives with...

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Bibliographic Details
Main Authors: Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Translational Medicine
Subjects:
Histone deacetylase 11
Intracellular survival
Interleukin 10
Mitophagy
Macrophage
Mitochondrial reactive oxygen species
Online Access:https://doi.org/10.1186/s12967-025-06161-7
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https://doi.org/10.1186/s12967-025-06161-7

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