Pleiotropic Effects of PCSK9 Inhibitors on Cardio-Cerebrovascular Diseases

Pleiotropic Effects of PCSK9 Inhibitors on Cardio-Cerebrovascular Diseases

Cardiovascular disease (CVD) and ischemic stroke (IS) are the primary causes of mortality worldwide. Hypercholesterolemia has been recognized as an independent risk factor for CVD and IS. Numerous clinical trials have unequivocally demonstrated that reducing levels of low-density lipoprotein cholest...

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Bibliographic Details
Main Authors: Zhenzhen Li, Lin Zhu, Yeqiong Xu, Yiting Zhang, Yukai Liu, Huiling Sun, Shuo Li, Meng Wang, Teng Jiang, Junshan Zhou, Qiwen Deng
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
pleiotropic effects
proprotein convertase subtilisin-kexin type 9
central nervous system
cardiovascular system
lipid metabolism
atherosclerosis
Online Access:https://www.mdpi.com/2227-9059/12/12/2729
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