Free Methylglyoxal and Lactate Produced and Released by Cultured Cancer and Non-Cancer Cells: Implications for Tumor Growth and Development

Free Methylglyoxal and Lactate Produced and Released by Cultured Cancer and Non-Cancer Cells: Implications for Tumor Growth and Development

We have previously shown that in cancer patients, free methylglyoxal (MG), a side-product of glycolysis, is recovered from tumors at significantly higher levels than from their corresponding non-cancerous tissues. We also recently confirmed our initial experimental finding that in these patients, fr...

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Bibliographic Details
Main Authors: Dominique Belpomme, Philippe Irigaray, Jean-Marc Alberto, Clément Poletti, Charlotte Hinault-Boyer, Stéphanie Lacomme
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
methylglyoxal
lactate
Warburg effect
glycolysis
tumor growth
cancer cells
Online Access:https://www.mdpi.com/2073-4409/14/12/931
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