Regenerative potentials of bone marrow mesenchymal stem cells derived exosomes or its combination with zinc in recovery of degenerated circumvallate papilla following surgical bilateral transection of glossopharyngeal nerve in rats

Regenerative potentials of bone marrow mesenchymal stem cells derived exosomes or its combination with zinc in recovery of degenerated circumvallate papilla following surgical bilateral transection of glossopharyngeal nerve in rats

Abstract Background Taste buds’ innervation is necessary to sustain their cell turnover, differentiated taste buds and nerve fibers in circumvallate papilla (CVP) disappear following glossopharyngeal nerve transection. Normally, taste buds recover to baseline number in about 70 days. Bone marrow ste...

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Bibliographic Details
Main Authors: Eman Mohamed Salem, Hamdy Rizk, Yara S. Abouelela, Abdelbary Prince, Adel Fathy Tohamy, Nawal A. Lasheen, Bassant A. Ezzat, Sana Mostafa
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Oral Health
Subjects:
BM-MSC-derived exosomes
Glossopharyngeal nerve
Peripheral nerve injury
Circumvallate
Taste buds
Regeneration
Online Access:https://doi.org/10.1186/s12903-024-05050-7
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https://doi.org/10.1186/s12903-024-05050-7

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