Proteasome inhibitors related thrombotic microangiopathy: a systematic and comprehensive review

Abstract Proteasome inhibitors (PIs) are crucial in treating multiple myeloma but carry a risk of thrombotic microangiopathy (TMA), especially with carfilzomib use. This systematic review includes 44 studies with 115 cases of PI-induced TMA, where carfilzomib was implicated in 101 cases. Treatment a...

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Bibliographic Details
Main Authors: Can Chen, Yiwei Li, Pengfei Shi, Shenxian Qian
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-024-01182-9
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