Systematic characterization of horizontally transferred biosynthetic gene clusters in the human gut microbiota using HTBGC‐Finder

Systematic characterization of horizontally transferred biosynthetic gene clusters in the human gut microbiota using HTBGC‐Finder

Abstract The human gut microbiota contains biosynthetic gene clusters (BGCs) that encode bioactive secondary metabolites, which play pivotal roles in microbe‐microbe and host‐microbe interactions and serve as a rich source of pharmaceutical lead compounds. Understanding the horizontal transfer of BG...

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Bibliographic Details
Main Authors: Jiacheng Wu, Xiao Yang, Lanlan Zhao, Ziyun Li, Guoping Zhao, Lei Zhang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:iMetaOmics
Subjects:
biosynthetic gene clusters
gut microbiome
horizontal gene transfer
metagenomics
quorum sensing
Online Access:https://doi.org/10.1002/imo2.62
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https://doi.org/10.1002/imo2.62

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