Polymeric nanoparticles loaded with vincristine and carbon dots for hepatocellular carcinoma therapy and imaging

Abstract Chemotherapy for hepatoblastoma is limited by organ toxicity and poor outcomes, prompting the search for new, more effective treatments with minimal side effects. Vincristine sulfate, a potent chemotherapeutic, faces challenges due to P-glycoprotein-mediated resistance and its systemic toxi...

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Bibliographic Details
Main Authors: Walaa Fawaz, Abdulsamie Hanano, Hossam Murad, Amal Yousfan, Ibrahim Alghoraibi, Jameela Hasian
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-75332-1
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