Computational prediction of protein interactions in single cells by proximity sequencing.

Proximity sequencing (Prox-seq) simultaneously measures gene expression, protein expression and protein complexes on single cells. Using information from dual-antibody binding events, Prox-seq infers surface protein dimers at the single-cell level. Prox-seq provides multi-dimensional phenotyping of...

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Bibliographic Details
Main Authors: Junjie Xia, Hoang Van Phan, Luke Vistain, Mengjie Chen, Aly A Khan, Savaş Tay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011915&type=printable
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