Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics

Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics

Abstract Cystic echinococcosis (CE) is a worldwide zoonotic public health issue. The reasons for this include a lack of specific therapy options, increasing antiparasitic drug resistance, a lack of control strategies, and the absence of an approved vaccine. The aim of the current study is to develop...

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Main Authors: Jadoon Khan, Asma Sadiq, May M. Alrashed, Nosheen Basharat, Syed Nadeem Ul Hassan Mohani, Tawaf Ali Shah, Kotb A. Attia, Aamer Ali Shah, Hayat Khan, Ijaz Ali, Arif Ahmed Mohammed
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Molecular and Cell Biology
Subjects:
Cystic echinococcosis
Multi-epitope vaccine
Echinococcus granulosus Antigen B (EgAgB)
Cytotoxic T lymphocytes
B-cell epitopes
pIB2-SEC13-mEGFP expression vector
Online Access:https://doi.org/10.1186/s12860-024-00524-6
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https://doi.org/10.1186/s12860-024-00524-6

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