Transcription factor EB enhances macrophage autophagy and reverses endotoxin tolerance

Transcription factor EB enhances macrophage autophagy and reverses endotoxin tolerance

Objective‍　‍To investigate the role of transcription factor EB (TFEB) in endotoxin-tolerant macrophages. Methods‍　The RAW264.7 cells were divided into blank group (DMEM medium), LPS 5 group (5 ng/mL LPS treatment for 4 h), LPS 100 group (100 ng/mL LPS treatment for 4 h), and tolerance group (5 ng/mL...

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Bibliographic Details
Main Authors: YANG Ting, LIU Xin
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-04-01
Series:陆军军医大学学报
Subjects:
sepsis
immunosuppression
endotoxin tolerance
transcription factor eb
autophagy
Online Access:https://aammt.tmmu.edu.cn/html/202410042.html
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