USP11 promotes lipogenesis and tumorigenesis by regulating SREBF1 stability in hepatocellular carcinoma

USP11 promotes lipogenesis and tumorigenesis by regulating SREBF1 stability in hepatocellular carcinoma

Abstract Background The relationship between hepatocellular carcinoma (HCC) metastasis and cancer metabolism reprogramming is becoming increasingly evident. Ubiquitin-specific protease 11 (USP11), a member of the deubiquitinating enzyme family, has been linked to various cancer-related processes. Wh...

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Bibliographic Details
Main Authors: Yongkang Xu, Jiayu Zeng, Kan Liu, Dan Li, Shenglan Huang, Shumin Fu, Mao Ye, Si Tao, Jianbing Wu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
Hepatocellular carcinoma
USP11
SREBF1
Lipogenesis
Tumorigenesis
Online Access:https://doi.org/10.1186/s12964-024-01926-x
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https://doi.org/10.1186/s12964-024-01926-x

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