Membrane-Mediated Action of Phosphodiesterase 5 Inhibitors

<b>Background/Objectives</b>: Phosphodiesterase 5 (PDE5) inhibitors, sildenafil, vardenafil, and tadalafil, activate the cyclic guanosine monophosphate pathway resulting in vascular smooth muscle relaxation. They have been tested for a broad variety of conditions from cancer to Alzheimer...

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Bibliographic Details
Main Authors: Anna I. Malykhina, Svetlana S. Efimova, Olga S. Ostroumova
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/17/5/563
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