Dual-responsive nanoparticles targeting ACE-II senescence for therapeutic mitigation of acute lung injury

Abstract Acute lung injury (ALI) is a life-threatening condition characterized by severe pulmonary dysfunction, with alveolar type II epithelial cell (ACE-II) senescence playing a pivotal role in its progression. In this study, we developed pH/reactive oxygen species (ROS) dual-responsive nanopartic...

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Bibliographic Details
Main Authors: Linlin Gao, Fushuang Zheng, Zhiling Fu, Wei Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03382-2
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