Defluorinative Cyclization of Enamides with Fluoroalkyl Halides Through Two Vicinal C(sp3)─F Bonds Functionalization

Defluorinative Cyclization of Enamides with Fluoroalkyl Halides Through Two Vicinal C(sp3)─F Bonds Functionalization

Abstract Introducing distinctive functional groups to expand the structural diversity and improve the intrinsic properties of parent molecules has been an essential pursuit in organic chemistry. By using perfluoroalkyl halide (PFAH) as a nontraditional, readily available, ideal 1,2‐difluoroalkenyl c...

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Bibliographic Details
Main Authors: Yu‐Lan Chen, Wei Han, Yuan‐Yuan Ren, Mengtao Ma, Danhua Ge, Zhi‐Liang Shen, Kai Guo, Xue‐Qiang Chu
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
1,2‐difluoroalkenyl group
C─F bond functionalization
defluorinative cyclization
fluoroalkyl halides
oxazole
Online Access:https://doi.org/10.1002/advs.202404738
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https://doi.org/10.1002/advs.202404738

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