Overexpression of hsa-HLA-DRB1 may delay diabetic wound healing and angiogenesis by regulating miRNA_12118 and FLT-1

Abstract We investigated the role and mechanism of hsa-HLA-DRB1 in the development and progression of diabetic foot ulcers. High-throughput sequencing was performed on three normal foot trauma tissues and diabetic foot ulcer tissues. The circRNAs with significant differences were identified. The dow...

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Bibliographic Details
Main Authors: Chao Bai, Wenwen Yang, Jianghao Yan, Guangwei Qi, Liuyu Yang, Qingrui Wu, Jieguang Peng, Jun Luo, Tao Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03906-8
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