Suppression of human and rat 17β-hydroxysteroid dehydrogenase 1 by isothiazolinone-based disinfectants: Insights into mechanism and implications for hormonal homeostasis
Isothiazolinone disinfectants constitute a class of broad-spectrum antimicrobial agents due to the pandemic of COVID-19. The aim of this study was to assess the impacts of six distinct isothiazolinone disinfectants on the activity of 17β-hydroxysteroid dehydrogenase 1 (17β-HSD1) in humans and rats,...
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| Main Authors: | Chuhang Chi, Chaochao Gong, Yunbing Tang, He Zhu, Qian Zhang, Yang Zhu, Shaowei Wang, Ren-shan Ge, Xiaoheng Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325005846 |
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