Azathioprine metabolite levels and outcomes during pregnancies with rheumatic disease

Objective Despite widespread use of azathioprine (AZA) during pregnancy, no studies evaluated the impact of pregnancy on AZA metabolites 6-thioguanine nucleotide (6-TGN) and 6-methylmercaptopurine nucleotide (6-MMPN) disposition in rheumatic diseases. This study characterises changes in AZA metaboli...

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Bibliographic Details
Main Authors: Valerie Smith, Amanda Eudy, Stephen Balevic, Megan Clowse, Catherine A Sims
Format: Article
Language:English
Published: BMJ Publishing Group 2024-05-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/11/1/e001036.full
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