Distinct mRNA expression profiles and miRNA regulators of the PI3K/AKT/mTOR pathway in breast cancer: insights into tumor progression and therapeutic targets

Distinct mRNA expression profiles and miRNA regulators of the PI3K/AKT/mTOR pathway in breast cancer: insights into tumor progression and therapeutic targets

BackgroundBreast cancer remains a leading cause of mortality among women, driven by the molecular complexity of its various subtypes. This study aimed to investigate the differential expression of genes and miRNAs involved in the PI3K/AKT/mTOR signaling pathway, a critical regulator of cancer progre...

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Main Authors: Tomasz Sirek, Katarzyna Król-Jatręga, Przemysław Borawski, Nikola Zmarzły, Dariusz Boroń, Piotr Ossowski, Olga Nowotny-Czupryna, Kacper Boroń, Dominika Janiszewska-Bil, Elżbieta Mitka-Krysiak, Beniamin Oskar Grabarek
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
breast cancer
miRNA
PI3K/Akt/mTOR pathway
molecular marker
mRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1515387/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1515387/full

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