Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs

Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs

ABSTRACT Fusobacterium nucleatum (F. nucleatum) is an oral commensal bacterium that can become pathogenic and is associated with periodontitis, adverse pregnancy outcomes, and colorectal cancer (CRC). MicroRNAs are conserved, non-coding RNA molecules that regulate gene expression and are detected in...

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Bibliographic Details
Main Authors: Syam Jeepipalli, Aravindraja C, William Duncan, V. M. Krishna, Bikash Sahay, Edward K. L. Chan, L. Kesavalu
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSystems
Subjects:
F. nucleatum
periodontal disease
miRNAs
CRC miRNAs
machine learning models
Online Access:https://journals.asm.org/doi/10.1128/msystems.01732-24
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https://journals.asm.org/doi/10.1128/msystems.01732-24

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