Marine-Derived Alternariol Suppresses Inflammation by Regulating T Cell Activation and Migration

Marine-Derived Alternariol Suppresses Inflammation by Regulating T Cell Activation and Migration

T cells play pivotal roles in inflammation’s initiation and progression. Exploring natural compounds that regulate T cell function is crucial for preventing and treating inflammation. Herein, we report that Alternariol (AOH), a marine-derived secondary metabolite, exerts an anti-inflammatory activit...

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Main Authors: Chenfeng Liu, Fudie Gu, Zhengbiao Zou, Fengli Wang, Dashuai Li, Jing Song, Yazhen Hong, Xuhui Wu, Xianwen Yang, Wen-Hsien Liu, Guangming Liu, Yu Zhou, Qingmei Liu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Marine Drugs
Subjects:
alternariol
CD4<sup>+</sup> T cells
inflammation cytokines
lung injury
cell migration
Online Access:https://www.mdpi.com/1660-3397/23/3/133
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