Improving butenyl-spinosyn production in Saccharopolyspora pogona through combination of metabolic engineering and medium optimization

Butenyl-spinosyn is a high-quality biological insecticide produced by Saccharopolyspora pogona that effectively targets a broad range of insect pests. However, the large-scale production of this insecticide is hindered by its low yield. Herein, based on prior comparative genomic analysis, five mutat...

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Bibliographic Details
Main Authors: Xueli Zhao, Haisong Lu, Sen Peng, Haifeng Hang, Waleed Aldahmash, Muath Q. Al-Ghadi, Weihua Tang, Jiang Pei, Wan Xun, Meijin Guo, Ali Mohsin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1561042/full
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