Dual-Mechanism Gastroretentive Tablets with Encapsulated Gentian Root Extract

Dual-Mechanism Gastroretentive Tablets with Encapsulated Gentian Root Extract

<b>Background/Objectives:</b> This study aimed to develop gastroretentive tablets based on mucoadhesive–floating systems with encapsulated gentian (<i>Gentiana lutea</i>, Gentianaceae) root extract to overcome the low bioavailability and short elimination half-life of gentiop...

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Bibliographic Details
Main Authors: Jelena Mudrić, Ljiljana Đekić, Nemanja Krgović, Đorđe Medarević, Katarina Šavikin, Milica Radan, Nada Ćujić Nikolić, Tijana Ilić, Bojana Vidović, Jelena Đuriš
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
double emulsion
solid lipid microparticles (SLMs)
quality by design
trehalose
in vitro digestion
gentiopicroside
Online Access:https://www.mdpi.com/1999-4923/17/1/71
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