Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways

Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways

Abstract Myocarditis, an inflammatory heart disease, often leads to severe cardiac dysfunction, including dilated cardiomyopathy and sudden death. Current treatments for myocarditis remain limited, necessitating the exploration of new therapeutic approaches. Liraglutide, a glucagon-like peptide-1 re...

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Bibliographic Details
Main Authors: Lijuan Zhang, Lishuai Han, Yang Lu, Quanzhou Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Liraglutide; myocarditis
NOD-like receptor family Pyrin domain containing 3
Nuclear transcription factor-κB
Glucagon-like peptide type 1
Online Access:https://doi.org/10.1038/s41598-025-12715-y
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https://doi.org/10.1038/s41598-025-12715-y

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