Cell graph analysis in hepatocellular carcinoma: predicting local recurrence and identifying spatial relationship biomarkers

Abstract A whole pathology section contains approximately 1,000,000 cells of various types, this large-scale heterogeneity of cells and non-cellular constituents constructs a mutually competitive community. Conventional pixel-based visual processing techniques are insufficient to accurately capture...

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Main Authors: Yizhe Yuan, Ziyin Zhao, Xin Fang, Qing Zhang, Wenqing Zhong, Midie Xu, Gongqi Li, Rushi Jiao, Heng Yu, Ruoxi Wang, Shuyu Liu, Weitao Zu, Bingsen Xue, Yuze Chen, Chengxiang Wang, Ya Zhang, Minghui Liang, Bing Han, Cheng Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01042-0
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