Decoupled tricarboxylic acid cycle and glycolysis of Corynebacterium glutamicum combined with acetate supply promote high-yield biosynthesis of l-homoserine

l-Homoserine is a valuable intermediate with broad applications in the food, pharmaceutical, and chemical industries. Although Corynebacterium glutamicum has been engineered for the efficient biosynthesis of l-homoserine, both production efficiency and glucose conversion remain suboptimal. In this s...

Full description

Saved in:
Bibliographic Details
Main Authors: Daobin Wang, Lu Xu, Junwen Yuan, Ruisi Wu, Xiyao Cheng, Jidong Liu, Ning Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-12-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X25001097
Tags: Add Tag
No Tags, Be the first to tag this record!