Direct conversion of urine-derived cells into functional motor neuron-like cells by defined transcription factors

Abstract Direct cell-type conversion of somatic cells into cell types of interest has garnered great attention because it circumvents rejuvenation and preserves the hallmarks of cellular aging (unlike induced pluripotent stem cells [iPSCs]) and is more suitable for modeling diseases with strong age-...

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Bibliographic Details
Main Authors: Hiroaki Nagai, Masayo Saito, Hidehisa Iwata
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-73759-0
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