Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling study

Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling study

Background In patients with colorectal cancer (CRC), the therapeutic effects of conventional immune checkpoint inhibitors targeting the adaptive immune system are largely limited to those with microsatellite instability-high tumors. Meanwhile, new immunotherapies targeting the innate immune system a...

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Main Authors: John Marshall, Sanjay Goel, Yan Yang, Emil Lou, Joanne Xiu, Hiroyuki Arai, Francesca Battaglin, Heinz-Josef Lenz, W Michael Korn, Jingyuan Wang, Shivani Soni, Wu Zhang, Joshua Millstein, Priya Jayachandran, Nishant Gandhi, Michael J Hall, Davendra Sohal, Sandra Algaze, Benjamin A Weinberg, Jae Ho Lo, Richard Goldberg, Aaron James Scott, Jimmy J Hwang
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/11/e010326.full
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