Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature
Objective. The optimal management of pediatric patients with arterial ischemic stroke (AIS) is not known. Despite this, goal-oriented, time-sensitive therapies geared to rapid reestablishment of arterial blood flow are occasionally applied with beneficial effects. The inconsistent approach to AIS is...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2010/497326 |
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| author | Jose Irazuzta Kevin J. Sullivan |
| author_facet | Jose Irazuzta Kevin J. Sullivan |
| author_sort | Jose Irazuzta |
| collection | DOAJ |
| description | Objective. The optimal management of pediatric patients with arterial ischemic stroke (AIS) is not known. Despite this, goal-oriented, time-sensitive therapies geared to rapid reestablishment of arterial blood flow are occasionally applied with beneficial effects. The inconsistent approach to AIS is in part due to a lack of knowledge and preparedness.
Methods. Case report of a 12-year-old male with right middle cerebral artery (MCA) occlusion resulting in dense left hemiplegia and mutism and review of the literature. Intervention(s). Mechanical thrombectomy, intra-arterial administration of rt-PA, vasodilators, and platelet inhibitors, and systemic anticoagulation and subsequent critical care support.
Results. Restoration of right MCA blood flow and complete resolution of neurologic deficits. Conclusion. We report the gratifying outcome of treatment of a case of AIS in a pediatric patient treated with hyperacute therapies geared to arterial recanalization and subsequent neurologic critical care and review the pertinent literature. Guidelines for the emergency room management of pediatric AIS from prospective, randomized trials are needed. |
| format | Article |
| id | doaj-art-79879a9659ef49fe9694192094a0005e |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-79879a9659ef49fe9694192094a0005e2025-02-03T01:08:57ZengWileyNeurology Research International2090-18522090-18602010-01-01201010.1155/2010/497326497326Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the LiteratureJose Irazuzta0Kevin J. Sullivan1Division of Pediatric Critical Care Medicine, University of Florida Health Science Center at Jacksonville and The Wolfson Children's Hospital, 800 Prudential Drive, Jacksonville, FL 32207, USADivision of Pediatric Critical Care Medicine, University of Florida Health Science Center at Jacksonville and The Wolfson Children's Hospital, 800 Prudential Drive, Jacksonville, FL 32207, USAObjective. The optimal management of pediatric patients with arterial ischemic stroke (AIS) is not known. Despite this, goal-oriented, time-sensitive therapies geared to rapid reestablishment of arterial blood flow are occasionally applied with beneficial effects. The inconsistent approach to AIS is in part due to a lack of knowledge and preparedness. Methods. Case report of a 12-year-old male with right middle cerebral artery (MCA) occlusion resulting in dense left hemiplegia and mutism and review of the literature. Intervention(s). Mechanical thrombectomy, intra-arterial administration of rt-PA, vasodilators, and platelet inhibitors, and systemic anticoagulation and subsequent critical care support. Results. Restoration of right MCA blood flow and complete resolution of neurologic deficits. Conclusion. We report the gratifying outcome of treatment of a case of AIS in a pediatric patient treated with hyperacute therapies geared to arterial recanalization and subsequent neurologic critical care and review the pertinent literature. Guidelines for the emergency room management of pediatric AIS from prospective, randomized trials are needed.http://dx.doi.org/10.1155/2010/497326 |
| spellingShingle | Jose Irazuzta Kevin J. Sullivan Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature Neurology Research International |
| title | Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature |
| title_full | Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature |
| title_fullStr | Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature |
| title_full_unstemmed | Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature |
| title_short | Hyperacute Therapies for Childhood Stroke: A Case Report and Review of the Literature |
| title_sort | hyperacute therapies for childhood stroke a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2010/497326 |
| work_keys_str_mv | AT joseirazuzta hyperacutetherapiesforchildhoodstrokeacasereportandreviewoftheliterature AT kevinjsullivan hyperacutetherapiesforchildhoodstrokeacasereportandreviewoftheliterature |