Associations of SEMA7A, SEMA4D, ADAMTS10, and ADAM8 with KRAS, NRAS, BRAF, PIK3CA, and AKT Gene Mutations, Microsatellite Instability Status, and Cytokine Expression in Colorectal Cancer Tissue

Associations of SEMA7A, SEMA4D, ADAMTS10, and ADAM8 with KRAS, NRAS, BRAF, PIK3CA, and AKT Gene Mutations, Microsatellite Instability Status, and Cytokine Expression in Colorectal Cancer Tissue

Semaphorins (SEMAs), ADAM, and ADAMTS family members are implicated in various cancer progression events within the tumor microenvironment across different cancers. In this study, we aimed to evaluate the expression of SEMA7A, SEMA4D, ADAM8, and ADAMTS10 in colorectal cancer (CRC) in relation to the...

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Main Authors: Błażej Ochman, Piotr Limanówka, Sylwia Mielcarska, Agnieszka Kula, Miriam Dawidowicz, Wiktor Wagner, Dorota Hudy, Monika Szrot, Jerzy Zbigniew Piecuch, Jerzy Piecuch, Zenon Czuba, Elżbieta Świętochowska
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Current Issues in Molecular Biology
Subjects:
semaphorin 7A (SEMA7A)
ADAM (a disintegrin and metalloprotease) proteins
ADAMTS10
ADAM8
SEMA4D
colorectal cancer (CRC)
Online Access:https://www.mdpi.com/1467-3045/46/9/609
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