High expression of THY1 is a prognostic marker for gastric Cancer: Deciphering its transcriptional regulation as a component of the Epithelial–mesenchymal transition

High expression of THY1 is a prognostic marker for gastric Cancer: Deciphering its transcriptional regulation as a component of the Epithelial–mesenchymal transition

Gastric cancer (GC) remains one of the leading causes of cancer-related mortality worldwide, with high molecular heterogeneity contributing to its poor prognosis. Among potential biomarkers, THY1 is associated with aggressive tumor behavior and poor patient outcomes. However, the transcriptional mec...

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Bibliographic Details
Main Authors: Paulo Rohan, Everton Cruz dos Santos, Pedro Leite Azevedo, Jessica Oliveira da Conceição, Eliana Abdelhay, Renata Binato
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biochemistry and Biophysics Reports
Subjects:
Gastric cancer
THY1
Regulatory networks
Epithelial–mesenchymal transition
Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825001372
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