RETRACTED: Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

RETRACTED: Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

To formulate novel chitosan (CS)-coated–PLGA–nanoparticles (NPs) using a central composite design approach and use them in order to improve brain bioavailability for catechin hydrate (CH) through direct nose-to-central nervous system (CNS) delivery for the evaluation of a comparative biodistribution...

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Bibliographic Details
Main Authors: Niyaz Ahmad, Rizwan Ahmad, Ridha Abdullah Alrasheed, Hassan Mohammed Ali Almatar, Abdullah Sami Al-Ramadan, Mohd Amir, Md Sarafroz
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
catechin hydrate
chitosan-coated–PLGA–nanoparticles
epilepsy
UHPLC-MS/MS
brain bioavailability and pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/12/3/203
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