Direct synthesis of N-trifluoromethyl amides via photocatalytic trifluoromethylamidation
Abstract N-CF3 amides are promising targets for pharmaceutical and agrochemistry. Unfortunately, there is a defluorination problem of N-CF3 amine starting materials when using common amide bond formation method. Recently, elegant alternative approaches emerged. However, none have used the well known...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60130-8 |
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