Characterizing HIV-1 Tropism and Key Positions within the V3 Loop Using Random Forest Analysis
Abstract HIV-1 exhibits tropism for the CCR5 and/or CXCR4 receptors, which are essential for viral entry into CD4 cells. With the advent of coreceptor antagonists, understanding HIV-1 tropism has become crucial for patient management. The V3 loop, a highly variable region of approximately 35 amino a...
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| Main Authors: | Karenn Evangelista Miranda, Letícia Martins Raposo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto de Tecnologia do Paraná (Tecpar)
2025-03-01
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| Series: | Brazilian Archives of Biology and Technology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000100303&lng=en&tlng=en |
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