Characterizing HIV-1 Tropism and Key Positions within the V3 Loop Using Random Forest Analysis

Abstract HIV-1 exhibits tropism for the CCR5 and/or CXCR4 receptors, which are essential for viral entry into CD4 cells. With the advent of coreceptor antagonists, understanding HIV-1 tropism has become crucial for patient management. The V3 loop, a highly variable region of approximately 35 amino a...

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Bibliographic Details
Main Authors: Karenn Evangelista Miranda, Letícia Martins Raposo
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2025-03-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000100303&lng=en&tlng=en
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