Gut microbiota modulates lung gene expression and metabolism to aid SD rats in adapting to low-pressure hypoxia

Gut microbiota modulates lung gene expression and metabolism to aid SD rats in adapting to low-pressure hypoxia

ABSTRACT Hypoxia has long posed a serious threat to the health of both animals and humans, causing respiratory acidosis, metabolic disorders, systemic inflammation, oxidative stress damage, and other issues, thereby endangering life and limiting development in high-altitude areas. Gut microbiota pla...

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Bibliographic Details
Main Authors: Zheng Chen, Shatuo Chai, Yuxia Ding, Kaiyue Pang, Tanqin Dong, Dongwen Dai, Jianmei Wang, Shuxiang Wang, Shujie Liu
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
hypoxic pulmonary hypertension
gut microbiota
SCFAs
hypoxia adaptation
inflammation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00045-25
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https://journals.asm.org/doi/10.1128/spectrum.00045-25

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