Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel

Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel

Abstract Long-duration spaceflight creates a variety of stresses due to the unique environment, which can lead to compromised functioning of the skeletal and immune systems. However, the mechanisms by which organisms respond to this stress remain unclear. The present study aimed to investigate the i...

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Main Authors: Yui Okamura, Kei Gochi, Tatsuya Ishikawa, Takuto Hayashi, Sayaka Fuseya, Riku Suzuki, Maho Kanai, Yuri Inoue, Yuka Murakami, Shunya Sadaki, Hyojung Jeon, Mio Hayama, Hiroto Ishii, Yuki Tsunakawa, Hiroki Ochi, Shingo Sato, Michito Hamada, Chikara Abe, Hironobu Morita, Risa Okada, Dai Shiba, Masafumi Muratani, Masahiro Shinohara, Taishin Akiyama, Takashi Kudo, Satoru Takahashi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Spaceflight
Microgravity
Thymus
Spleen
Bone
Gene expression
Online Access:https://doi.org/10.1038/s41598-024-79315-0
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https://doi.org/10.1038/s41598-024-79315-0

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