Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma

Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma

Abstract Background Patients diagnosed with gallbladder carcinoma (GBC) accompanied by hepatic metastasis exhibit unfavorable prognoses generally. Mitochondrial dysfunction promotes cellular transformation and cancer cell survival implicating its importance in cancer development. Previous studies ha...

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Bibliographic Details
Main Authors: Ruopeng Liang, Xiaoxue Zhang, Shitao Wu, Jing Liu, Yunpeng Zhai, Chaojie Lin, Zhenya Wang, Yi Zhang, Hao Chen, Rongtao Zhu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Biology Direct
Subjects:
DNM1L
USP3
Gallbladder cancer
Deubiquitination
Mitochondrial homeostasis
Online Access:https://doi.org/10.1186/s13062-025-00637-8
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https://doi.org/10.1186/s13062-025-00637-8

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