Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness.

Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness.

Transcriptional regulatory networks play a central role in optimizing cell survival. How DNA binding domains and cis-regulatory DNA binding sequences have co-evolved to allow the expansion of transcriptional networks and how this contributes to cellular fitness remains unclear. Here we experimentall...

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Bibliographic Details
Main Authors: Adi Hendler, Edgar M Medina, Anastasiya Kishkevich, Mehtap Abu-Qarn, Steffi Klier, Nicolas E Buchler, Robertus A M de Bruin, Amir Aharoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006778&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006778&type=printable

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