Activity of imipenem/relebactam against KPC-producing Klebsiella pneumoniae and the possible role of Ompk36 mutation in determining resistance: an Italian retrospective analysis

Activity of imipenem/relebactam against KPC-producing Klebsiella pneumoniae and the possible role of Ompk36 mutation in determining resistance: an Italian retrospective analysis

Abstract Background Antimicrobial resistance in Enterobacterales represents a substantial threat in modern clinical practice and the collection of data on the efficacy of new molecules is of paramount importance. Our study aimed to analyse the in vitro activity of imipenem/cilastatin/relebactam (IMI...

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Main Authors: Emanuele Palomba, Agnese Comelli, Francesca Saluzzo, Federico Di Marco, Elisa Matarazzo, Noemi Lo Re, Alessandra Bielli, Chiara Silvia Vismara, Antonio Muscatello, Marianna Rossi, Daniela Maria Cirillo, Alessandra Bandera, Andrea Gori
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Imipenem/relebactam
KPC
Carbapenem-resistant
Klebsiella pneumoniae
Online Access:https://doi.org/10.1186/s12941-025-00792-w
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https://doi.org/10.1186/s12941-025-00792-w

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