Cellular senescence and other age-related mechanisms in skeletal diseases

Abstract Cellular senescence and its senescence-associated secretory phenotype (SASP) represent a pivotal role in the development of skeletal diseases. Targeted elimination or rejuvenation of senescent cells has shown potential as a therapeutic strategy to reverse age-related skeletal senescence and...

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Bibliographic Details
Main Authors: Ke Li, Sihan Hu, Hao Chen
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-025-00448-7
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