A preliminary study on regulation of macrophages phenotype and anti-tumor effects by PRTN3

Objective To investigate the effect of knockdown PRTN3 on polarization phenotype and anti-tumor function of macrophages in breast cancer. Methods A mouse monocyte/macrophage cell line(RAW264.7) with knockdown of PRTN3 was constructed. The mRNA and protein levels of PRTN3 were detected by RT-qPCR and...

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Bibliographic Details
Main Author: GUO Anjing, CHEN Chong, LUO Yunping
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2025-06-01
Series:Jichu yixue yu linchuang
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Online Access:https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-6-701.pdf
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