Infectious Spleen and Kidney Necrosis Virus Triggers Ferroptosis in CPB Cells to Enhance Virus Replication

Infectious Spleen and Kidney Necrosis Virus Triggers Ferroptosis in CPB Cells to Enhance Virus Replication

The role of ferroptosis—a novel iron-dependent programmed cell death pathway—in infectious spleen and kidney necrosis virus (ISKNV) infection remains poorly understood. Here, we demonstrate that ISKNV infection induces ferroptosis in CPB cells. Following ISKNV challenge, CPB cells exhibited hallmark...

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Bibliographic Details
Main Authors: Qiushuang Zhang, Ouqin Chang, Qiang Lin, Hongru Liang, Yinjie Niu, Xia Luo, Baofu Ma, Ningqiu Li, Xiaozhe Fu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Viruses
Subjects:
ferroptosis
ISKNV
viral replication
GPx4
ACSL4
Online Access:https://www.mdpi.com/1999-4915/17/5/713
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