Prenatal valproic acid on the basis of gestational diabetes also induces autistic behavior and disrupts myelination and oligodendroglial maturation slightly in offspring

Abstract Introduction Gestational diabetes mellitus (GDM) and prenatal exposure to valproic acid (VPA) are both constitute risk factors for autism in progeny. Notably, dysmyelination in the corpus callosum serves as a prominent element connecting GDM and autism in the white matter lesions. Objective...

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Bibliographic Details
Main Authors: Maolin Li, Zhifei Qiao, Jizheng Li, Hongli Zhou, Dong Huang, Yan Cai, Xiaolong Li, Zuo Zhang, Jianyun Zhou, Jiyin Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03450-z
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