Silibinin attenuates ferroptosis in acute kidney injury by targeting FTH1

Silibinin attenuates ferroptosis in acute kidney injury by targeting FTH1

Acute kidney injury (AKI) is primarily caused by renal ischemia-reperfusion injury (IRI), which is one of the most prevalent triggers. Currently, preventive and therapeutic measures remain limited. Ferroptosis plays a significant role in the pathophysiological process of IRI-induced AKI and is consi...

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Main Authors: Yijian Deng, Liying Zeng, Huaxi Liu, Anna Zuo, Jie Zhou, Ying Yang, Yanting You, Xinghong Zhou, Baizhao Peng, Hanqi Lu, Shuai Ji, Ming Wang, Yigui Lai, Hiu Yee Kwan, Xiaomin Sun, Qi Wang, Xiaoshan Zhao
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Redox Biology
Subjects:
Acute kidney injury
Silibinin
Ferritin heavy chain 1
Ferroptosis
Ferritinophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003380
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