MicroRNA210 Suppresses Mitochondrial Metabolism and Promotes Microglial Activation in Neonatal Hypoxic–Ischemic Brain Injury

MicroRNA210 Suppresses Mitochondrial Metabolism and Promotes Microglial Activation in Neonatal Hypoxic–Ischemic Brain Injury

Neuroinflammation is the major contributor to the pathology of neonatal hypoxic–ischemic (HI) brain injury. Our previous studies have demonstrated that microRNA210 (miR210) inhibition with antisense locked nucleic acid (LNA) inhibitor mitigates neuroinflammation and provides neuroprotection after ne...

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Bibliographic Details
Main Authors: Shirley Hu, Yanelly Lopez-Robles, Guofang Shen, Elena Liu, Lubo Zhang, Qingyi Ma
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
neuroinflammation
mitochondrial dysfunction
microglia
hypoxia–ischemia
Online Access:https://www.mdpi.com/2073-4409/14/15/1202
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