Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes

Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes

Tendinopathy is a common musculoskeletal disorder in which a significant number of patients do not attain effective therapeutic outcomes. The extent of the inflammatory response and the dynamics of collagen synthesis metabolism are critical factors that influence the intrinsic self-repair capacity o...

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Bibliographic Details
Main Authors: Danmei Li, Shuai Li, Shukun He, Hongpu He, Guangxun Yuan, Binbin Ma, Yijun Zhang, Chengjie Yuan, Zhiqin Liu, Zhenhan Deng, Jian Xu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-05-01
Series:Bioactive Materials
Subjects:
Tendinopathy
Macrophage
Tendon-derived stem cell exosomes
Tendon-derived extracellular matrix
Hydrogel
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25000167
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