The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer
Background. The utility of repeat EUS in patients with suspicion for pancreatic cancer after non-diagnostic EUS-FNA study is not well established. Aim. Determine the accuracy of repeat EUS-FNA in patients with suspected pancreatic cancer and prior non-diagnostic EUS-FNA. Methods. Retrospective cohor...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2010/268290 |
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| author | Mark Nicaud Wei Hou Dennis Collins Mihir S. Wagh Shailendra Chauhan Peter V. Draganov |
| author_facet | Mark Nicaud Wei Hou Dennis Collins Mihir S. Wagh Shailendra Chauhan Peter V. Draganov |
| author_sort | Mark Nicaud |
| collection | DOAJ |
| description | Background. The utility of repeat EUS in patients with suspicion for pancreatic cancer after non-diagnostic EUS-FNA study is not well established. Aim. Determine the accuracy of repeat EUS-FNA in patients with suspected pancreatic cancer and prior non-diagnostic EUS-FNA. Methods. Retrospective cohort study. Results. From 2002 to 2008 in our institution 28 patients underwent repeat EUS-FNA for suspected pancreatic cancer. Initial EUS showed a pancreatic mass in 24 (85.71%), no mass in 3 (10.71%) and possible mass in 1 (3.58%). FNA was performed and was negative for malignancy in all patients. Repeat EUS showed pancreatic mass in 27 patients (96.42%) and no mass in 1 (3.58%). FNA was performed in all patients and cytology was positive for malignancy in 6 (21.43%). Out of the 28 patients, 17 (60.71%) were eventually confirmed to have cancer. Overall repeat EUS-FNA correctly determined the true final status in 17 out of 28 patients providing sensitivity for the diagnosis of cancer of 35% (95% CI 14%–62%), specificity 100% (95% CI 72%–100%), and overall accuracy of 61%, (95% CI 28%–72%). Conclusion. Repeat EUS-FNA provides reasonable accuracy and may be worthwhile in patients with suspected pancreatic cancer who had had prior negative EUS-FNA. |
| format | Article |
| id | doaj-art-788a347ade434de4bde9cfc15a69b86a |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-788a347ade434de4bde9cfc15a69b86a2025-02-03T05:46:41ZengWileyGastroenterology Research and Practice1687-61211687-630X2010-01-01201010.1155/2010/268290268290The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic CancerMark Nicaud0Wei Hou1Dennis Collins2Mihir S. Wagh3Shailendra Chauhan4Peter V. Draganov5Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, Room HD 602, P.O. Box 100214, Gainesville, FL 32610-0214, USADepartment of Epidemiology and Health Policy Research, University of Florida, Gainesville, FL 32611, USADivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, Room HD 602, P.O. Box 100214, Gainesville, FL 32610-0214, USADivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, Room HD 602, P.O. Box 100214, Gainesville, FL 32610-0214, USADivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, Room HD 602, P.O. Box 100214, Gainesville, FL 32610-0214, USADivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, Room HD 602, P.O. Box 100214, Gainesville, FL 32610-0214, USABackground. The utility of repeat EUS in patients with suspicion for pancreatic cancer after non-diagnostic EUS-FNA study is not well established. Aim. Determine the accuracy of repeat EUS-FNA in patients with suspected pancreatic cancer and prior non-diagnostic EUS-FNA. Methods. Retrospective cohort study. Results. From 2002 to 2008 in our institution 28 patients underwent repeat EUS-FNA for suspected pancreatic cancer. Initial EUS showed a pancreatic mass in 24 (85.71%), no mass in 3 (10.71%) and possible mass in 1 (3.58%). FNA was performed and was negative for malignancy in all patients. Repeat EUS showed pancreatic mass in 27 patients (96.42%) and no mass in 1 (3.58%). FNA was performed in all patients and cytology was positive for malignancy in 6 (21.43%). Out of the 28 patients, 17 (60.71%) were eventually confirmed to have cancer. Overall repeat EUS-FNA correctly determined the true final status in 17 out of 28 patients providing sensitivity for the diagnosis of cancer of 35% (95% CI 14%–62%), specificity 100% (95% CI 72%–100%), and overall accuracy of 61%, (95% CI 28%–72%). Conclusion. Repeat EUS-FNA provides reasonable accuracy and may be worthwhile in patients with suspected pancreatic cancer who had had prior negative EUS-FNA.http://dx.doi.org/10.1155/2010/268290 |
| spellingShingle | Mark Nicaud Wei Hou Dennis Collins Mihir S. Wagh Shailendra Chauhan Peter V. Draganov The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer Gastroenterology Research and Practice |
| title | The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer |
| title_full | The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer |
| title_fullStr | The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer |
| title_full_unstemmed | The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer |
| title_short | The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer |
| title_sort | utility of repeat endoscopic ultrasound guided fine needle aspiration for suspected pancreatic cancer |
| url | http://dx.doi.org/10.1155/2010/268290 |
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