A multicellular self-organized probiotic platform for oral delivery enhances intestinal colonization

Abstract Stable gut colonization of probiotics is essential for sustained therapeutic effects, however traditional oral probiotic supplements often fail to adapt to the gut environment. Here, based on the observation that multicellular microcolonies instead of planktonic bacteria display a more adva...

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Bibliographic Details
Main Authors: Hua Liu, Zhijie Chen, Qiaowen Lin, Yi Chen, Liwen Hong, Jie Zhong, Zhengwei Cai, Zhengting Wang, Wenguo Cui
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62349-x
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