Remodeling of the cardiac striatin interactome and its dynamics in the diabetic heart

Remodeling of the cardiac striatin interactome and its dynamics in the diabetic heart

Abstract Diabetic cardiomyopathy (DbCM) is a silent and complex condition involving numerous signaling pathways that impair cardiomyocyte metabolism and cardiac performance. Striatin (STRN) is a multifaceted protein that binds metabolic proteins, yet its role in diabetic heart remains unexplored. He...

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Main Authors: Stephanie Chacar, Wael Abdrabou, Cynthia Al Hageh, Liaqat Ali, Thenmozhi Venkatachalam, Pierre Zalloua, M.-Saadeh Suleiman, Frank Christopher Howarth, Ali A. Khraibi, Moni Nader
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Diabetic cardiomyopathy
Striatin interactome
Diabetes
Signalosomes
Metabolic Disease
Online Access:https://doi.org/10.1038/s41598-025-91098-6
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https://doi.org/10.1038/s41598-025-91098-6

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